By Robin Holliday

For hundreds of years humans were questioned by way of the inevitability of human getting older. for many of the second one half the 20 th century getting older remained a secret, or an unsolved organic challenge. on the finish of the twentieth century a awesome clinical discovery emerged. It was once now not a unmarried discovery within the ordinary feel, since it was once in accordance with a chain of vital interconnected insights over really a protracted time period. those insights made it attainable for the first actual time to appreciate the organic purposes for getting older in animals and guy. it could possibly already be acknowledged, despite the fact that, that the numerous observations and insights that specify getting older should not authorised as validated wisdom for a very long time. the sphere continues to be packed with scientists, and non-scientists, who're simply chuffed to move on speculating concerning the 'mystery' of getting older. the purpose of this booklet is to dispel lack of know-how via explaining in non-technical language what are the explanations for getting older and the parable of over the top prolongation of lifestyles.

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One part of this interaction is the ability of animals to detoxify harmful chemicals in their diet, which is a particularly important function of the liver. This organ produces a wide range of specific enzymes which can break down to harmless derivatives a huge variety of organic compounds synthesised by plants. This detoxification is an essential maintenance mechanism, since many plants in our normal diet contain chemicals which are routinely removed by the liver, or by other tissues. During evolution plants may come up with a new toxic chemical, but in turn the animal evolves an additional defence.

Other animals breed repeatedly over quite long periods. In these cases, the fertile adult body must be maintained in a normal healthy state for years or decades. However, there is no example of a complex animal in which the body is maintained indefinitely. Sooner or later ageing and death supercede reproduction. It has sometimes been argued that some large fish or reptiles do not age in the usual sense. These long-lived animals usually increase in size throughout their lifespan, in other words, they have pools of dividing cells that keep growing and slowly increasing body weight.

Unfortunately, because there are so many cells in the body, the probability that at least one of them will eventually become cancerous becomes quite high. Of course, similar mutations may be occurring in all cells, but the vast majority do not reach the point where growth regulation is affected. Cancer is such an obvious body abnormality, that it is not surprising that it is labelled as a disease. Nevertheless, many old people who die from some other cause, commonly have several or many incipient tumours.

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